Product Name

Trehalose 6,6′-dimycolate from Mycobacterium bovis

General description

Cord factor is a glycolipid released from Mycobacterium that becomes toxic and antigenic when it interacts with cell surface lipids.

Synonym

6,6’-Di-O-mycoloyl-α,α-trehalosefrom Mycobacterium bovis, Cord factor from Mycobacterium bovis

Assay

≥97%(6,6′-mycolate esters basis)

CAS Number

61512-20-7

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to Off-White Powder

Optical activity

[α]25/D 32 to 35 °, c = 1% (w/v) in chloroform/methanol/water (10:9:1)

l  Biological Information

Biochem/Physiol  Actions

Cord factor is a glycolipid released from Mycobacterium that becomes toxic and antigenic when it interacts with cell surface lipids. It activates macrophages to release inflammatory cytokines and induces thymic atrophy and granuloma formation in lung and other organs. It is responsible for the necrosis and cavitation observed in secondary tuberculosis.

l  Storage

Storage temp.

−20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov